Unveiling the living organ with cell biology printer: printing vein (1)

Åœ — äº¬æ — July 21, message, according to Wired magazine reported that organ transplant that saved the lives of many people, but this technology there are not enough organs, it is difficult to avoid rejection, and other ills.

Now, with the United States biotechnology company Organovo has developed a biological printer, using patients ' own cells "print" vein, these problems will be solved. Perhaps one day, the doctor can "on-demand print" living organs, including blood vessels and complete organ.

Organovo senior scientists-Shepard (Ben Shepherd) said: "at the moment, we are the ' print ' blood vessels.

This week we print a lot, but also in understanding how to make them function very, can print features more reliable vessel. "Most of the organs of the human body are covered with dense venous, print the vascular tissue of ability to get the full organ, is a key step.

Print out the vein is about to begin to test on animals, and ultimately implement human clinical trials.

If everything went well, a few years later, you may be able to use their own cells grown "print" organization alternative go bad veins, such as frequent drug injection chemical deterioration of the vein. Print complete organ not only faced with technical barriers, the first organ biology printer from development, test, production to the market, the cost of up to hundreds of millions of dollars, not to mention any companies in United States food and Drug Administration (FDA) approval of difficulties encountered.

United States Carolina Advanced Biomedical manufacturing Center Director Vladimir-Mironov (Vladimir Mironov), said: "If Organovo company can raise enough money, the company will have as first biological printing company success potential, but it need time to prove it.

"The following is Organovo company displayed throughout the process of biological print vein.

1. biological reactor

MBR bioreactor using a special chemical mixture, help cells become strong vascular tissue

Shepherd is a bioreactor placed in incubators, and growth medium for reaction, after a few days.

Bioreactor using a special chemical mixture, help cells become strong vascular tissue, the mixture is similar to cell growth in the human body.

2. stem cells

Stem cells after training, the number of stem cells will make rapid increase once a sufficient number of cells that can be used centrifuges from the growth medium separation, compressed into granular

Shepherd will stem cells taken from a pool of liquid nitrogen.

After training, the number of stem cells will increase rapidly and then injected into the bio-printer. Ultimately, these cells from patients with various parts of the body-fat, bone marrow and skin cells — check out the role of the vein. After thawing in stem cells, they will train in growth medium. This step enables stem cell constant reproduction and growth, this allows for the formation of vein. Growth medium also take advantage of special chemicals that stem cells grow into the required type, in this case is the blood cells. Once you make a sufficient number of cells that can be used centrifuges from the growth medium separation, compressed into granular.