Saturday, November 27, 2010

Scientists develop Nano car from cancer drugs directly into the

Åœ — äº¬æ — ¶é — ' news, 23 September, according to physicist organization network reported that the current treatment of cancer chemotherapy is an efficient method, but it also has some bad side effects, such as sick, liver toxicity and immune system function.

Tel Aviv University's Dan · Peel, limona · Magritte and his colleagues have developed a way to direct the chemotherapy drugs to cancer cells, to avoid interaction with healthy cells "Nano car", this approach may increase the effects of chemotherapy while reducing side effects.

PIR explains: "this vehicle like a cluster bomb.

"Inside the Nano car is carrying chemotherapy drugs of nano-particles, which can take these chemotherapy drugs directly into cancer cells. According to Pere describes, this kind of nanoparticles vehicle can be used to treat many different types of cancer, such as lung cancer, leukemia, colon, breast and uterine cancer, pancreatic cancer, even several types of brain tumors. For this new nanoparticles for tumor treatment aspects of the application of articles, published in the journal of biological materials.

This drug delivery platform, the key is used to make this kind of cluster nano-particles of shell molecules: hyaluronic acid (Hyaluronan).

Hyaluronic acid is a can be many types of cancer cells by receptor recognition of sugar molecules. PIR said: "when the Nano carrier and cell receptor interaction experiences happen when affected by structural change, chemotherapy drugs will be directly released to the cancer cells. "He explained that the study results to chemotherapy for more focus on the fight against disease cells.

As a result of nano-particles react only to cancer cells, so the surrounding healthy cells against the effects of chemotherapy.

PIR, the Nano car itself is a natural fat molecule, nano-particles play a role, in the body to break down, so this kind of therapy than current chemotherapy method is more secure. Through suffering from cancer in mice experiments revealed that use hyaluronic acid package, which is full of paclitaxel nanoparticles, prevent tumor growth than non-paclitaxel (Taxol carrying an albumin nanoparticles) nanoparticles.

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