Sunday, March 27, 2011

Unveiling the next medical technology: wandering in the blood of micro robot

Since the application started bloodletting, healthcare technology has come a long way.

The future of healthcare technology and even will make today's most widely used therapy has become obsolete. A similar capture cancer of nanoparticles and virus of lasers and light heart monitors, medical technology breakthrough makes targeting technology has begun to enter the new era. Take advantage of targeted therapy techniques, drugs will be directly guided most part needed, treatment is a healthy body tissues also will no longer be involved, the disease has just been signs of a wire can also be detected in real-time.

Call tone to physical examination of lasers

From 1954, alcohol measuring instrument has been used to determine whether alcohol or drunk drivers.

United States Colorado University physicist suiye military apply this concept to a whole new areas: medical diagnosis. As long as breath a sigh of relief, he designed the device can detect thousands of different biological molecules, but also sensitive enough to pick up perhaps represents the specific disease of rare biological molecules. On the outbound content from a snapshot, you can check out from cancer to cystic fibrosis, and many other diseases.

This instantaneous diagnosis by a field called "optical frequency comb" laser-driven, can issue a broadband optical waveguides and air compounds react.

Optical frequency comb is used to measure the different color (or frequencies) of light, its comb line is adjusted to specific elements of a clear frequency or optical activity. While the entire optical frequency comb can cover a wide range of spectral range, its a lot like a rainbow of color, to monitor the thousands of different molecules. Suiye military said, when in regular intervals optical frequency comb icon, you see the "Rainbow", once breath molecules pass through the "Rainbow", the set of resonance frequency makes the optical frequency comb looks like a missing tooth. When many respiratory molecules are also monitored by then, so you can be provided with specific diseases of high reliable information. For example, the last of the illustration shows the presence of carbon monoxide, hydrogen peroxide and nitric oxide, breath could suffer from asthma.

Suiye military said, patients do not have to spend a few days to wait for the test results, "just a minute, you'll know what's going on".

Pre-emptive early tumor surgery

The world's scientists are committed to the development of new cancer treatment method, these new methods including more effective chemotherapy and better bone marrow transplant program, and the United States John Hopkins University chemists Thomas • Ken Kessler is committed to using the more advanced and effective new treatments to replace all of these efforts.

Ken Kessler and Dartmouth College of colleagues together to reveal a way to prevent cancer-early formation in amazing ways.

Just like earthquakes and avalanche, cancer is the entire sequence of instability caused by the results, such as abnormal cells in the wrong time in wrong place; cellular and intercellular communication were broken; cell blindly for proliferation and differentiation. Ken Kessler through use of a known as CD Juan DO — Im of oleanolic acid analogues compounds for the treatment of health organizations, in the laboratory to disturb the sequence. From plant acid CDDO — Im activates the toxic compounds from cells — compounds (may cause cancer by making a DNA mutation) Elimination of natural enzymes. CDDO — Im also has other oleanolic acid derivatives as anti-inflammatory activity. All of these makes CDDO — Im with cancer prevention role. CDDO — Im prevention of aflatoxin-induced cancer than so far known other cancer prevention agents are more effective.

Ken Kessler said that the next few years, Im still CDDO — cannot be applied to the clinic.

But you can give patients a day, a healthy person can choose according to their own genetic susceptibility and environmental conditions of use of this approach. Researchers aim is to prevent very early cancer occurrence of significant change.

Real-time monitoring of blood pressure of implantable Nanowires

In the doctor's Office to conduct routine blood pressure checks, maybe will soon become a thing of the past.

United States Georgia Institute physicist wangzhonglin has devised an implantable of nanowires, can continuously measuring blood pressure fluctuation, the patient at home will be able to track their own physical condition.

The sensor works? researchers use of Nanowires has two important properties: it is both a semiconductor, but is a piezoelectric material.

This means that, if the imposition of an external mechanical force the Nanowire, such as vasoconstriction of external forces, nanowires will produce a line of electric field. This field presence affect the nanowires conductivity, which can be measured. If the conductivity changes, also indicates that blood pressure is changing.

This technology more than ever, technology has improved significantly.

Legacy device in arm needs a considerable wrapped in cloth, but the new sensor can be implanted in his arm and real-time monitoring. Patients wearing a watch-like device to record data, once an exception occurs, the watch will be able immediately to patients or doctors send alarm signal.

This implant-Nanowires may also have other potential applications.

Scientists often need to automatically measure very small pressure variables. For example, in hundreds of kilometres of natural gas pipelines, similar sensors can help predict potential explosion risk.

Against superbugs-infrared laser

Antivirals and antibiotics have been HIV and Staphylococcus aureus that root bacteria from the first line of Defense, but anti-virals and antibiotics are also a number of serious drawbacks: antiviral medicines can wreak havoc in the pancreas and liver, and antibiotics are on fixed-resistant strains has no effect.

In response, the United States, Arizona State University physicist Professor KT • has developed a multi-function treatment tools: one can kill bacteria and viruses without harming the surrounding tissue of infrared laser.

This method of innovation is to laser to destroy the mechanical way, instead of the pathogen to chemical or biological means.

Researchers use lasers in fineBacteria or virus protein shell manufacturing a large vibration, activate it to a sufficiently high energy State, leading to weak ties with the shell. Because of the mammalian cell does not have such a case, this method will be able to keep the patients body intact of the destruction of those unwanted germs.

Professor said that preliminary results of in vitro tests indicate that the laser effectively destroyed the AIDS virus.

Based on the progress made so far, researchers in the two years the hospital used such laser is optimistic.

No side-effects of microbubbles targeted drug delivery

Drugs can follow the design uses to treat disease, however, when the drugs are indiscriminate be absorbed into the blood vessels can also be triggered the debilitating side effects.

For example, chemotherapy nausea and tablets can be raised in alopecia, and antibiotics can cause fatigue and shortness of breath.

In order to help patients overcome side effects, Philips's pharmaceutical sector is developing a similar to target missile delivery systems.

Philips scientists will put drug particles of fluorocarbon gas micro-bubble, and then injected into the patient's blood. When the bubbles reach the treatment target area, the technical staff of a high power ultrasonic pulse, and led to the formation of bubbles bubbles burst, the resonance-release drug particles.

The project's lead scientist kelisiduofu • Hall said that the micro-bubble will take a more rational way to pay the amount of chemicals, high concentration of the correct drug to need treatment.

One day will be able to use the bubble wrapped drugs to treat prostate cancer, breast cancer and fights, and eliminates the often treat these diseases must pay the price of intense body.

Wandering in the blood of micro robot

At present, like a tumor resection or unblock blocked arteries, and so on operation requires a presence in the hospital patients with a very long time.

But Israel Technology Institute of engineers Vaux Dade • Solomon developed a mosquito size robot will enable doctors to the purposes of these operations do not need to leave a large incision, therefore can make patients recover more quickly.

Creativity derived from the last century 80 's game with the laser surgery: micro-task of a clue, Solomon made robot is only 1 mm in diameter.

This is called "the robot, ViRob" it'd hooked metal arm to grasp the venous and arterial, and take advantage of built-in cutter cut a little organizations. In most normal operation, the probe for manipulation, doctors must take an out of the body of an external handle, but there is no "ViRob" such restrictions. Robot once injected into the vein, the operator can place the external magnetic field tuned to different frequencies to manipulate its speed and direction.

Solomon said, because you don't have to physically external manual control "Rob" Vi Juan, so doctors can access another surgery cannot reach the area.

Doctors can even to a patient at home for remote operation. He predicted that the professionals will be in 5 years using the robot to biopsy and procedures such as vascular repair.

Posted in heart of wireless ECG

The morning after, as long as they could wake up to the chest with a super light patch, we will be able to ensure the computer all day time monitoring your heart beat.

This is the Netherlands Horst Center image incentive experts developed the next generation of ECG monitor, in size and simplicity are than similar products.

Research Program Manager Julian • Pan Desmond said, use the normal electrocardiogram monitor must be an electrode Plug and test to pocket a fixed box connected the new appliance is a significant step forward, to the entire body surface wear.

Hidden in the secret behind the ultra-small detector is a chip, the chip can be monitored from patch-electrode signal and transmit wirelessly to a computer to read the signals.

This type of intelligent chips with low power for optimal performance, without the need for bulky battery compartment, so as to apply to preventive medicine.

Mr Desmond said, a less invasive techniques. This flexible wireless device just simply attached to the user can at any time in the chest, his heart rate monitoring.

Science fiction come true Nano Cancer Fighter

The 1960s, one called the "singular" science fiction film journey, the story is a Soviet scientists fled to the United States, because he was a spy of cerebrovascular damage in the face.

5 United States doctors be reduced into a fainter, injection into scientists to vascular surgery in the body. United States MIT engineer sangue Tower • batia will this science fiction becomes reality, she developed programming can get straight into nanoparticles for cancer cells, and to the nearby release chemotherapy drugs.

Batia doctorate at the Massachusetts Institute of technology, specializing in how micro-manufacturing process for human tissue engineering to restore liver function, and micro-fabrication technology was originally used in the manufacture of semiconductor chips.

Later, batia sidetracked, want to use a variety of approaches to development had been used for coating and computer technology used to manufacture small body parts. Thus, this miniature cancer killer — Nano-particle was born.

The particle surface is a substance, to the cancer cells to "home", one of the categories of substances containing peptides, peptides can be used with the tumor blood vessels, protein binding, so they become toxic chemotherapy directly into the tumor cells "striker" toxic drugs travels in systemic side effects.

Batia, the nanoparticles to get the United States food and Drug Administration's approval to enter the clinical application, 5 to 10 years.

At the same time, researchers are developing a way to track tumor is doing and what's new material to learn about the tumor is more intrusive or staging, so that the proliferation of cancer can be treated with before.

Biodegradable scaffold of stem cells

Injured location for emergency repair of the lost tissue, stem cells need a stent to growth, but like plastic such artificial material cannot become such branch

Frame, because the body will put this class of artificial materials marked as foreign substances and rejected.

Ravi • Kane is the United States, New York, Rensselaer Polytechnic Institute of biology of the engineer, he used the Brown algae in a complex natural carbohydrates alginate, produce biodegradable scaffold of stem cells, and thus avoid the above problems.

Embed in brackets is called micro-bubble of release over time, as well as micro beads are called alginate lyase of carbon in vivo, the last embedded scaffolds in adjustable rate degradation.

Kane hope this algae bracket enables doctors to stem cells implantation of directly injured tissue, such as the healthy bone stem cells implantation of the fracture site, or the neural stem cells implantation in the Alzheimer brain lesion area.

The future of the series is "two in one" package, you can simultaneously transmit stem cells and drug molecules. Kane said, this is a modular system, still have space on the bracket, you can also apply other types of particles placed in it.

Deep brain internal magnetic pulse

20% of depressive patients on treatment of drug fluoxetine (Prozac) is not responding, the traditional final treatment means will have to use electric shock therapy.

Recently, researchers around the world are beginning to delve into a promising new therapy: Transcranial Magnetic Stimulation (TMS). Use of TMS, attached to the scalp of metal coil produces magnetic pulses in the brain produces a small current to stimulate the brain and depression-related area of nerve cells without damaging surrounding gray matter.

This spring, this treatment method adds more power, because Israel Brainsway company announced that they have successfully tested the technology of the latest, the depth of the TMS.

The company's CEO, Phil Woods • cable, standard TMS device for magnetic field can only be extended to the cerebral cortex of about half an inch (about 1.3 cm). But the depth of the TMS in magnetic field coil can be projected onto the skulls of some points around, can stimulate a deeper neurons. This means that, for the first time, the clinician can be emotional debugging on play an important role in brain positioned deep limbic system-directed therapy. To date, the unit has achieved very good results, in 64 accepting depth TMS therapy, 40% achieved distinct clinical rehabilitation.

The company is lobbying for the United States food and Drug Administration approved the use of this device, Phil also is evaluating depth TMS on Parkinson's and influence of the cerebral cortex of the darker the applicability of other neurological diseases.

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