Sunday, December 12, 2010

Optical coherence tomography system concerns

At present, China's patients with coronary heart disease more than 40 million people.

It is not difficult to imagine that the high incidence of coronary heart disease for diagnostic device development and a great opportunity. In recent years, coronary heart disease clinical diagnostic equipment and technology of endless, echocardiography, helical computed tomography Imaging (MSCT) machine, high-resolution magnetic resonance imaging (MRI) machine and radionuclide imaging equipment and other non-invasive system, coronary angiography (CAG), intracoronary Ultrasound (IVUS), optical coherence tomography (OCT), virtual organization Imaging (VH), elastic graph, temperature chart (thermal image measuring plaque temperature), near-infrared spectroscopy, Raman Spectroscopy, intravascular MRI and coronary vascular mirror and other invasive systems and technologies. So, which method most potential clinical experts on the? one of the most right of speech. Beijing anzhen hospital Cardiology expert Professor Lu sz, recently told reporters that the focus of the study of coronary heart disease is the vulnerable plaque detection and discovery, while the optical coherence tomography Coronary lesions of extremely high resolution of any other existing imaging incomparable, thus this technology to become the 2008 clinical coronary heart disease and abroad the most "heat" of a new technology.

Very high resolution

In recent years, with percutaneous coronary intervention for rapid development of new diagnostic system came into being, which concern with intravascular ultrasound system, coronary vascular mirror, etc.

Conducted on coronary intravascular ultrasound, not only to determine the extent of coronary artery disease, and plaque stability, lumen-size, whether you need intervention are important reference value, is whether the judge involved after stent wall good, lesions covering, whether it is tear intima main tools in the world widely use. And coronary vascular microscope can be used to evaluate intima on bracket cover extent, the existence of a thrombus, currently in Japan some hospitals are applied. In 2001 the first abroad optical coherence tomography system in human coronary artery for high-definition images, the technology in the field of application of percutaneous coronary intervention reported gradually increased, now become attracted domestic and foreign experts highly concerned with one of the technology.

Prof. Lu sz said, optical coherence tomography is a new high resolution computed tomography imaging mode, its optical technology and hyper-sensitive detector one, using near-infrared to probe the Endovascular Micron structure, application of modern computer image processing, have extremely high resolution, can detect 65 ~ 70 micron imaging, better than any existing imaging technology.

Foreign researchers compared the Kubo T, optical coherence tomography system, coronary ultrasound systems and coronary vascular microscopic evaluation of lesions in patients with acute myocardial infarction. The results show that optical coherence tomography system check out plaque rupture of 73%, significantly higher than endoscopic coronary blood vessels (47%) and coronary ultrasound examination (40%). And optical coherence tomography system and backscatter technology and attenuation coefficient combines can better compare organizational characteristics. The technology and light and electron microscopy of histological structure has good relevance. This indicates that the system is expected to become the evaluation of unstable plaques and support the ideal means of treatment effectiveness. The study also shows that different observers with optical coherence tomography system observed the same lesion stents maximum diameter, area, stand wire and the extent of endometrial thickness of cover are the same. This explains the technology with good repeatability and accuracy.

Application value

Lu sz Professor told reporters that the concern is that the optical coherence tomography will be original in-stent vascular endothelialization concept changed to stent endometrium coverage concepts.

This technology allows you to explore the coverage area of thickness, organization, distribution and thrombosis, to judge the stent endometrium coverage level. And intravascular ultrasound compared it to judge the bracket induced rends, endometrial tissue detachment and bracket adherent bad aspects. Currently, the United States and Europe some heart Center main optical coherence tomography system to judge the coronary plaque, especially plaque fiber Cap thickness and lipid core; apply the technical judgment vascular rends and place the bracket on the wall bracket, bracket bare in Endovascular coverage of the endometrium, as well as support wire and vascular intimal; also adopts the system for evaluation of stenting in the acute phase of the wall bracket, with a clear stand on the mechanisms of vascular walls, Stent thrombosis, judgment of perioperative blood vessel damage; stent implantation after a few months to several years, using optical coherence tomography system evaluation Stenting in the medium and long term effects.

Promote the difficult

Although clinical experts at home and abroad on optical coherence tomography system of very positive, but every time near 15000 RMB check costs (all patients at their own expense) to allow the domestic many hospitals, related departments and patients can only be closed.

It is understood that, at present, China's only PLA General Hospital, beijingdianliyiyuan, Beijing anzhen hospital, second affiliated hospital of Harbin Medical University, medical college affiliated hospital five armed police has configured the optical coherence tomography system, has not a hospital examination cases reached more than 100 cases.

Beijing anzhen hospital in 2007, the purchase of domestic Radio 5 optical coherence tomography system, as of November 2008, the hospital has completed 30 cases of checks.

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