Our heavy ion deep cancer therapy clinical trial study starts

Recently, in the shallow tumor therapy clinical trial success based on the Chinese heavy ions in the treatment of cancer has made new progress, deep cancer therapy clinical trial study in modern physics, Chinese Academy of Sciences.

As of April 3, already have signed more than patients in clinical trials began in zhiyuanshu based in modern physics, Chinese Academy of Sciences of the Gansu province in heavy ion beam therapy cancer clinical research base to begin treatment. "The clinical trials still by Chinese Academy of Sciences Institute of modern physics and Lanzhou in Gansu province Cancer Hospital, Lanzhou Institute and other medical institutions, and the original combination of depth less than 2.5 cm of shallow cancer treatment trials, this is the depth of greater than 2.5 cm deep cancer clinical trials. "Modern physics, Chinese Academy of science and technology Deputy Commissioner Huzheng countries said. In November 2006, the Chinese Academy of Sciences Institute of modern physics and local health agencies to begin heavy ion shallow tumor therapy clinical trial research. Huzheng States that "has a 8 103 cases of shallow cancer clinical trials, efficacy was significant, indicating that the Chinese in heavy ion superficial treatment of human cancer clinical trial on the initial success. "In 2008, the new heavy-ion accelerator of Lanzhou cooling storage ring provides high energy heavy-ion beam treatment of deep tumor treatment Terminal in Chinese Academy of Sciences Institute of modern physics is built, and completed a beam test and the first cell and animal studies. Recently started heavy ion deep cancer therapy clinical trial research is on that basis.

Treatment of malignant tumours is haunting the world challenge.

Doctor of general use, though in the radiotherapy of cancer treatment on some show good results, but there is an obvious side effect, but in the course of treatment, will give the affected the surrounding healthy tissue causing greater damage. Unlike traditional radiation therapy for cancer e, X, compared to conventional x-ray, heavy ion beam with radiation damage to healthy tissue, the treatment course short, light cure rates high.

International advanced medical electronic technology is accelerating development (1)

Imagine this scene: a heart disease in the lungs is constantly producing effusion, this is the early symptoms of heart failure.

While the patient of an implantable sensor medical equipment through a Bluetooth enabled mobile phones at the same time with the patient and his doctors send signals to remind potential danger. Daydreaming?. This technology actually exists and is constantly improving, and the lack of a support infrastructure.

InCube company founders Mir Imran recently in Las Vegas 2009 International Consumer Electronics Show (CES) in a medical electronic discussion groups described above.

The participants discussed the implantable device of great potential, they can precisely and quickly monitoring and treatment is located anywhere in the world of chronic * disease patients, such as heart disease, epilepsy, diabetes and Parkinson's syndrome, etc.

In addition to the sensor implant, there are many more steps to improve people's health-care level.

Like insulin pumps and other equipment are already very mature, can offer services for all organs. Implantable Visual systems have also made significant progress. Micro electro mechanical systems (MEMS) and carbon nanotubes (CNT) nervous system implantation is providing human how to conduct large amounts of information.

Used for the diagnosis and treatment of many health problems of tools are being rapidly improved.

Some surgical instruments can be accessed through the catheter body almost every section. Sustained-release drug capsules are becoming more efficient, and enhanced diagnostic and therapeutic effect. External device can be worn on the treatment of applications is also very important, and lab-on-chip devices can quickly sampling, diagnosis and reporting of important medical tizheng patients.

Healthcare technology can meet the emergency needs.

Worldwide approximately 80% of healthcare costs for treatment of chronic diseases of the elderly. Approximately 6 million patients suffer from chronic diseases, such as chronic obstructive pulmonary disease (COPD), congestive heart failure and epilepsy-mental disorders etc. Longer life, lack of health care professionals and health care costs spiraling makes the situation worse.

"Single United States healthcare market on tat 2.5 trillion.

"Diamond Management & Technology Consultants company analyst Andrew Rocklin said," anyone not want to participate in this market will lose significant revenue potential. "But the effectiveness of the techniques demonstrated before a series of obstacles must be overcome, one of which is the healthcare system, including the United States and around the world, the need for a thorough reform.

Diabetes and heart disease Papuans

Debiotech company and ST (STMicrolectronics) jointly announced the company has developed the first disposable insulin pump Tablet prototype (Figure 1).

The use of Microfluidic MEMS technology of nano-pump has passed the initial testing stages, and since last summer started the mass production. Its size is the original one-fourth of the insulin pump equipment, worn on the skin is almost invisible.

This Nano pump use of continuous subcutaneous insulin injection (CSII) technology perfectly simulate the secretion of insulin by the pancreas, the simultaneous detection of naturally affect patient safety potential pump failure.

According to the two companies, and several times a day you must make separate insulin injection, it costs less, is a more attractive alternative technologies.

University of Michigan researchers Mark Meyerhoff is helping United States * military research laboratory develops implantable glucose sensor of subcutaneous, this sensor can real-time monitoring diabetes symptoms.

His use of polymers to the birth of low concentration of nitric oxide. As a surgical implant type current meter glucose sensor outer envelope, these materials have better bio-compatibility, because they can reduce the implantation of inflammation caused by the sensor. Cardiovascular disease is the cause of death and disability of the common factors. United States-third of deaths by including arrhythmia, heart disease, which would also encourage people to develop medical monitoring equipment and tools. Belgium IMEC company design wireless electrocardiogram (ECG) disk monitor is a device (Figure 2).

Shanghai medical information: pioneer of considerations (1)

How to convert all kinds of medical institutions to consolidate information systems, breaking information Islands, has been the medical industry information most headache problem.

In the new round of health care reform, cross-sector information system will become the innovation system. But how information technology can be used?

Building the patient-centric cross-hospital clinical information sharing system, through technical innovation, top-level design created a large hospital as well as vertical integration of information sharing and collaborative service mode.

Shanghai "hospital with a project" to clinical information sharing as a breakthrough, mitigation "costlier" issue, is an important medical reform initiatives and innovative mode of practice.

Suddenly as a night of spring.

Hospital correct respectable unprecedented powerful potential intervention medical information. Medical, this is the most recognized information sector hard nut to crack, what will happen?

The doctor without long waiting in the team, each time a referral without holding a stack of patient records, doctors in the diagnosis and treatment process can be intelligently medication safety reminder ...

This wonderful social scenes in Shanghai is well underway for the construction of the "hospital with the project" Chiang Kai-shek is becoming a reality.

Break between tangible and intangible hospital barriers, allowing isolated resource flows through the medical information for hospital information shared between, dredge limited medical resource provides collaborative services, Shanghai medical service will enter a new era of "intelligent networks".

Shanghai hospital with engineering covers Shanghai Shen Kang hospital development centre (hereinafter referred to as Shen Kang Center) belongs to the municipality of 23 three hospitals, using information technology to the hospital patients seeking information link to avoid unnecessary duplication of inspection, testing and medication, thereby significantly reducing the cost of medical treatment, palliative patients "difficulty, expensive" issue.

Shen Kang Centre is a public hospital reform Mo separately, as the pioneer of Shanghai Municipal Government of construction requirements, performed the duties of investor-owned asset, the municipal hospital in the State-owned assets investment, management, operation of duty and the responsibility of the Government of the construction.

In September 2005, Shen Kang AECT started brewing implementation hospital with projects, implementation of respective medical institutions clinical information sharing on the limited use of medical resources for consolidation. In October 2006, Shen Kang Center was the first launch Shanghai hospital with engineering system construction; in 2007, in Shanghai Science and Technology Commission of the Organization, and Wanda information co., Ltd., Ruijin hospital, changning district community health centre, zhabei district community health services administration Center, and other units with the application is a science and Technology Department of the "eleventh five-year" national science supported project support. After three years of construction, the project has achieved a 23 three hospitals and six branch of lateral sharing of medical information, and with the Shanghai changning, Minhang, Luwan, zhabei district-level health information on four platforms to achieve vertical Internet for horizontal and vertical two aspects of information exchange and business collaboration to build bridges to the new birth of healthcare service model laid the Foundation for information technology.

Forearmed, not pre is not set.

In the face of each hospital information system status of heterogeneous strong, Shanghai Science and Technology Commission works to promote the hospital with a well-planned layout: 2005 soft subjects on Hospital heterogeneous systems interconnection issues research; in 2006, in a single hospital applied digital health support platform (DOP) consolidation Yan Chai Hospital various heterogeneous systems of diagnosis and treatment of data, and then in Yueyang hospital, feikeyiyuan and children Medical Center application, after intensive Internet upload data to the hospital with Centre; 2006 over the same period in changning district implements regional medical information consolidation and sharing; 2007 organized Shanghai advantages apply to the Ministry of science and technology units to support projects; 2009 layout related topics to deepen the use of Internet sharing of medical information, provide the public with full health services and collaborative health care services. The layout of these projects, effectively supporting the Shanghai Municipal Hospital with works of construction.

The wisdom of the medical

Shanghai hospital with engineering focuses on integration of third-level hospital medical resources, share information, services, core is the benefit of people's livelihood.

This year's 65-year-old aunt is "three dry high" crowd.

15 years, she has been regularly to the city level designated hospitals for treatment. The long wait, complex registration consultation processes and billing, take medicine, iterative, traffic congestion, stairs and queued for old she became frustration.

Today, the stem of aunt himself Luwan district community health centers doctor, general practitioner community has long since passed the EHR (electronic health records) won her basic health records and personal information.

Through the initial diagnosis, the doctor advised her to tertiary hospital for further examination and confirmed, and through the hospital with engineering platform to issue electronic referral Ruijin hospital, direct booking the hospital's outpatient and biochemical and Imaging tests, aunt you no longer have to queue up clinic as before.

Stem aunt took 23 three accredited hospital hospital unified lianka, Ruijin hospital, clinic doctors through the hospital with a platform of "doctor workstation" will be able to directly access to her past in many hospitals do Biochemistry and radiology test report, direct diagnosis and prescription.

Convenient treatment processes, accurate diagnosis and treatment for dry aunt laugh-by-Word, and finally solved her broken heart for many years.

Use C # the development of electronic medical record system temperature graph

EMR (Electronic Medical Record, EMR) system is a digital technology, computer technology, communications technology, software engineering, technical, and other graphic images integrated multidisciplinary, high-tech projects.

The complete data, data processing, network transport, medical support, statistical analysis, etc. are all paper records.

Temperature is the electronic medical record system an important data, such as a patient's body temperature rises could allow clinicians to know the symptoms of patients with fever.

In the electronic medical record system, temperature single against user is hospital nurse. Nurses daily records of the patient's temperature, and other information, entry to the database, the system automatically generates single-electron temperature and draw a graph. Temperature graphs visually displays the patient's temperature, and other related data, and related diseases and to treat the combination of knowledge, as further diagnosis and determine treatment options.

I participate in the development of electronic medical record system under a large hospital's actual demand, on the .NET platform using C # language throughout development.

This article focuses on electronic medical record system temperature curve of the design and implementation.

1 the main function of electronic medical records system

This system according to the actual needs of the hospital, the main purpose is to capture patient data, so that it can provide clinicians with the diagnosis and decision-making information, further to the information to be used in clinical research.

System main features as shown in Figure 1.

2 temperature curve design and implementation of

2.1 thermometer generation

In the electronic medical record system, each hospital treatment of the patient in the hospital during a medical record number, this is a sign of patients determine code, usually in the database system as only the corresponding codes and keywords.

The patient's home nurses to patients for temperature, pulse, respiration, and various aspects of testing, will these data entry to electronic medical records system, the system automatically generates a single body temperature.

In the patient's temperature single, you need to record and analyze the patient's temperature transformation.

Temperature single information "temperature" and "pulse" and "breathe" the information to every 4 hours recording time, at 4 pm, 8 pm, 12, 16, 20, 24, when the time period. The "stool frequency," "the number or volume of urine" and "comprebensive" and "emissions" and "blood", "weight" and other information is recorded once a day. According to body temperature single information to 1 day to 1 unit, draw 1 days patients in various time periods of "temperature" and "pulse" and "breathing" of the curve changes, as well as record number of the "stool", "the number or volume of urine" and "consumption" and "emissions" and "blood", "weight" and other information. Whole body temperature chart 1 shows only 7 days. In your diagram with coordinates and curve describes the patient's temperature of continuous changes visually satisfying nurse to patient's temperature, respiration, pulse, and other information published and query needs. Figure 2 is a temperature single display interface.

2.2 temperature mapping

Temperature chart is based on the temperature of the auto-generated data.

Since the temperature chart show the patient at a time 7 days temperature changes, so the design of the page, on the length of time the patient through the page each time you skip 7 days to ensure the patient's temperature display of information integrity.

2.2.1 C # GDI + drawing

Temperature mapping from .NET base class set up GDI + implementation, the base class can be used to complete the custom drawing on the screen, the appropriate directive is sent to the graphic device driver, make sure that the display screen shows the correct output.

In GDI, identify the output device is to use object device context (DC).

The object stores information about a specific device, and can convert GDI API function calls to send to the device for instructions. Implementation of the function you want to use Paint to a GDI + drawing technique. By overriding the OnPaint Form class (PaintEventArgs e) to perform drawing operations.

In OnPaint (), the first reference from the PaintEventArgs in the paint graphics Graphics object.

Finally, call the base class's OnPaint () method.

When the application first starts, the first time a window appears, call the OnPaint (), there is no need in the constructor copies the drawing code.

Because the entire body figure comparison, but display window classified as 800 × 600, in order to be able to complete display temperature graph document, the document is out of the window, the notification window scroll bars appear in the right hand side.

To this end, the entire document as a range (1 800, 886) pixels, and in the form designer in the properties of the AutoScroll property is set to True. In this way, when the temperature chart more than window scroll bars automatically appear.

2.2.2 absolute coordinates to the relative coordinates transformation

In general the drawing code, because the rendering of the graphics area is less than the size of the window, there is no need for special attention.

Graphics instance by default is the coordinates are interpreted as relative to the window, it does not know the scroll bar. When you slide the scroll bars, Windows does not require the application to redraw the already displayed on the screen. Windows only pointed out the screen currently displayed content can smooth move to match the position of the scroll bar. For extra document parts in applications is first displayed, there is no draw that portion of the window, because in the scroll window, this part of the window area outside. This means that Windows requires ScrollShapeS application draws the region. It raises the paint event, put this region as cut a rectangle, in window and original graphic is displayed, it will appear a window with multiple graphics overlap, resulting in a graphic confusion.

The solution is to put the Graphics instance with the default coordinates to the coordinates relative to the coordinates that are relative to the upper-left corner of the window, not the upper-left corner of the start of the document, the absolute coordinates converted to relative coordinates.

Here in Figure 3 shows this conversion.

Solid rectangle marked with a screen area of borders and the border of the entire document.

The dotted rectangle marked attempt to draw a rectangle and ellipse. P tags to draw a random point. When you call drawing methods, providing the Graphics instance and from A point into a vector P point, the whole vector is represented as a Ponit instance. But actually need is from point B to point P of the vector. The problem is that here only know from A point into a vector point P, P relative to the coordinates of the upper-left corner of the document, and to document the P points drawing. Also know from point a to point b, of the vector is scrolled, it is stored in a property of the Form class AutoScrollPosition. Want to know from point b to point vector P only require vector subtraction. Graphics class of the TranslateTransform method can make these vector calculation. Here it transmit horizontal and vertical coordinates representing Windows drive gone, and the upper-left corner of the relative to the upper-left corner of the document of the vector (AutoScrollPosition property, it is a figure from a to B vector), and Graphics device considered window area relative to the document area, dealing with these coordinates. As long as the drawing code by adding the following statement: g.TranslateTransform (this.autoscrollpositiort.x this.autoscrollposition.y); you can solve the problem of transformation.

2.2.3 temperature diagram rendering technology

Temperature mapping according to body temperature in patient related information, using only C # GDI + to draw out the appropriate temperature graphs.

In the program first absolute coordinate and relative coordinate transformation, and then use the Pen class defines the brush, Brush class defines the brush color, for the need to fill in with a brush to fill, and then call the DrawLine method of the Graphics class to draw the line. In the DrawLine method, you offer the brush type, the segment start and end points coordinates and other parameters.

Temperature graph after initialization, according to pass from the thermometer of the patient number as your global variables in the diagram, the database query and the query results are converted to a coordinate, passed to the draw method of the DrawLine and FillEllipse, draw graphics.

Figure 4 is a temperature graph display interface.

2.2.4 temperature diagram page implementation

Because every time the body temperature chart only shows patients 1 week temperature conversion information, to display the 1 week prior to your information, you can use page functions.

The page features implemented using mainly used when reading data to Read () method. By Read () method to read data while the current pointer down one bit. Initially it is located in the data set before the first row, the first call to Read () will put the pointer on the first line, making it the current row. With each call to Read () causes the pointer to move down from the top down in order to obtain the dataset row. Code is as follows:

Where the variable n is the global variable from the scrolling buttons to be assigned.

To the current variable n minus 1 x 7 is required to skip the number of intervals, to date, the date for the data set filter, elects this week for the date stored in the array array.

3 conclusion

Electronic medical record is the hospital information development trend.

According to the requirements of the standardized HL7, the current domestic electronic medical research is far from perfect, it is necessary to work out perfect adaptation to the domestic use of hospital electronic medical record system also needs further study. This article on using C # drawing electronic medical record system temperature graph technology, tried to improve the electronic medical record system do useful attempt. Electronic medical record system-related research will be evolving and in-depth, and electronic medical record technology architecture and software process will become more and more mature.

Use of high-performance ADC creates a new magnetic resonance imaging of the send/receive architecture (1)

Summary: this article discusses magnetic resonance imaging (MRI) system works, the systematic use of hydrogen atoms in the magnetic field of the movement to form a clear medical images.

The article describes a typical magnetic field type and current high-resolution MRI system relies on superconducting magnets. This article also discusses appropriate arrange gradient coil formation process of 3D image and they and the interaction between the RF signal, MRI System block diagram.

Overview

Magnetic resonance imaging (MRI) system to provide a clear image of human tissue, System testing and treatment of hydrogen atoms in strong magnetic field resonance magnetic excitation in pulse fired the generated signal.

Hydrogen nuclei spin campaign determines its own intrinsic magnetic moment, in strong magnetic field, the hydrogen atoms are aligned.

Simplicity, you can put a static magnetic field of the hydrogen atom as a tensioning rope. Nucleus has a resonance frequency or "Larmor frequency", depending on local magnetic field strength. Like a rope under tension in external resonance occurs. In a typical 1.5T MRI magnetic field, the resonance frequency of the hydrogen atom to 64MHz.

Appropriate magnetic resonance excitation or RF Pulse excitation (frequency equal to hydrogen nuclei resonance frequency) to force the nuclear magnetic moment some or all of the effects of magnetic field is offset to the vertical plane.

Stop motivation, nuclear magnetic moment will be restored to the condition of a static magnetic field. Atomic nucleus in rearranging of release energy in the process, the resonance frequency (depending on field strength) of RF signals, MRI imaging system on the signal to be detected and form an image.

MRI imaging system block diagram

Who indicated that they will soon announce the arrival of an influenza pandemic

The World Health Organization (WHO), Assistant Director-General, Fukuda said on 9 November, WHO increasingly approaching announced an influenza pandemic, but first want to make sure that all is ready, avoid panic.

Fukuda on influenza a H1N1 influenza virus continues to spread.

Following the outbreak of April in North America, Australia after extensive outbreaks have been around 1000 cases.

Outside North America confirmed large crowd diffusion, will promote flu alert level from the current 5-level rose to the top-grade 6.

Fukuda said in a conference call: "in the past few days the situation varies greatly, very close to the influenza pandemic, or we are increasingly approaching announced a flu pandemic.

”

He said it would alert level to 6-level description of a new influenza spread of geographic range.

"This does not mean that the severity of the situation, or had serious increase in the number and proportion of increase than now.

”

In his view, declare influenza pandemic is not merely made an announcement that simple.

Who must ensure that countries have the capacity to cope with new situations, properly handle public reactions.

"One of the key problem is that we want people to know that after an influenza pandemic will not be ' excessive panic '.

We want them to know that the current outbreak is still relatively modest and so on. ”

He stated that who and its 193 Member States is intensifying the measures taken, such as the development of vaccines, antiviral stockpiling.

Semiconductor technology for next-generation medical equipment research and development (1)

Semiconductor company developed cutting-edge technology allows engineers to design can improve human health conditions of equipment.

Rapidly rising health care costs, obesity and chronic diseases of all kinds, as well as popular, the large increase in the elderly population, all of these factors on those users affordable and reliable to various medical equipment needs gradually increase, including patient care equipment, medical imaging equipment, as well as a variety of inspection instruments. In modern history, never to be what it is today, the semiconductor industry is for various medical device development paving, save countless lives, while also significantly reducing healthcare costs.

Previous major medical device has been redesigned into today's portable devices, some devices like mobile phones, size and even smaller.

But like the ultrasonic system for medical devices of this kind can only be used in the past, hospitals and medical clinics in big cities, and now has spread to rural small medical clinics and ambulances. With medical equipment of miniaturization and portable requirements evolve, in order to support including weight and more light and smaller portable systems, such as the next generation of medical devices, semiconductor manufacturers face huge challenges, they must develop integrated chip.

Patient monitoring system

Regardless of the patients in hospitals, care facilities for the continuous observation of critically ill patients, and the cost to less than traditional bed care system.

Usually the patient monitoring system including EKG (electrocardiogram), blood pressure, body temperature, blood oxygen saturation and respiration monitoring system, sometimes also includes AED (automated electric shock defibrillator) functionality in these systems often contain a high resolution ADC (ADC), low noise amplifier, instrument amplifier, and have been adopted in this field for many years in various combinations of analog functions. These are mature, high-performance system, major semiconductor manufacturers to put a lot of research and development of many innovative chip.

In these systems are equipped with the ward at the same time, they are also becoming more and more small, or even be able to fly to the patient's belt.

In the near future, EKG, blood pressure and activity monitoring with wireless communication technology that allows patients to stay in their homes, and patient safety key signs and reliable real-time monitoring, which will substantially reduce the total cost of care.

As the baby boom era was born people gradually entered the aging, need special care of the increasing number of elderly, home monitoring devices demand is rapidly increasing.

According to the World Health Organization information on the 2006 global 60 years of ageing population has reached 6.5 billion. By 2025, the figure is expected to be increased to 12 million. In the United States, 65 years and older population in the total population is already occupy a larger proportion than ever before, but in the 21st century will be steady growth.

"Because of the growing ageing population, chronic disease care costs will be fast growth," ADI Healthcare Division of global strategic marketing manager Paul Errico said, "today is home to the design of medical devices to be able to monitor blood pressure, blood sugar levels and heart rate, when the device appears in the doctor's warning.

This will eliminate or reduce patient frequently go to the clinic or hospital doctor's fees, resulting from the doctor or hospital for further patients bring Gospel. ”

To become a major component of health care management, patient monitoring systems and other equipment, as well as other essential patient information resources to achieve full interoperability.

Despite extensive interoperability also failed to materialize, but this has become a medical and information technology industries need to give priority to solving the problem. For example, a company named Continua Health Alliance organization is working with the technology industry, the medical equipment industry and the healthcare industry's leading enterprise cooperation in order to establish an interoperability solution system.

Medical imaging

As technology continues to improve, including CT (computer x-ray tomography) scanners, and ultrasound systems, medical imaging applications continue to grow, thus doctor's analysis and Diagnostics provide clearer and more precise image of the human body.

In the field of medical imaging, a single system of number of channels increasing, rendered fast also focus on semiconductor companies to improve integration and reduce power consumption, and lower the cost of each channel. Ultrasound, CT, MRI (magnetic resonance imaging) and PET (positron emission tomography scanners), etc, all of these high performance systems are driving the standard device in power, speed, accuracy and dynamic range wait performance progress.